PCA Health and Genetics - Articles

Deafness prevalence and pigmentation and gender associations in dog breeds at risk

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1		Deafness prevalence and pigmentation and gender associations in dog breeds at risk
1.1.		Abstract
1.2.		Introduction
		TABLE 1

2		Materials and methods

2.1.		Animals
2.2.		Hearing testing
2.3.		Pigmentation phenotypes
		TABLE 2
2.4.		Statistical analysis
		TABLE 3

3		Results

3.1.		Prevalence
3.2.		Gender
3.3.		Coat pigmentation
		TABLE 4
		TABLE 5
3.4.		Iris color
		TABLE 6
3.5.		Parental hearing status

4		Discussion
		TABLE 7
5		Acknowledgements
6		References

Deafness prevalence and pigmentation and gender

associations in dog breeds at risk

1.1. Abstract

Hearing function was tested in dogs from breeds at risk for pigment-associated

congenital sensorineural deafness – Dalmatian, English Setter (ES), English

Cocker Spaniel (ECS), Bull Terrier (BT), Australian Cattle dog ( ACD ), Whippet,

Catahoula Leopard dog, and Jack Russell Terrier.

Deafness prevalence was highest in Dalmatians and lowest in ECS.

Phenotype correlation studies were performed in breeds with >100 brainstem

auditory evoked responses (BAER) tested subjects.

No gender differences were observed.

No differences were seen between black- and liver-spotted Dalmatians,

among the ES roan color varieties, among the ECS parti varieties, or among

the ACD colour varieties. Blue eyes were positively associated and patches

were negatively associated with deafness in the Dalmatian. Blue eyes were

also associated with deafness in the ES and ECS. White BT were more likely

than colored BT to be deaf. Having one or more parent's ear deaf was

Published by Elsevier Science Ltd. Keywords: Deafness; Dog; Pigment ;

Piebald; Melanocyte